Chelsey Spriggs Lab
We study how viruses interact with their hosts to cause infection, as well as the relationship between viruses and cancer.
We study how viruses interact with their hosts to cause infection, as well as the relationship between viruses and cancer.
The Spriggs lab seeks to understand the cell biology of oncogenic and oncolytic viral infections. Specifically, we investigate the virus-host interactions mediating DNA viral entry, with particular interest in the steps required for these viruses to gain entry into the nucleus. Our lab uses a combination of classical biochemistry and molecular biology techniques with advanced microscopy to clarify the relationship between virus infection and cancer.