Two early-stage projects targeting HIV and obesity advance with philanthropic support
Two LSI researchers are launching projects to apply their basic science questions to public health challenges, with philanthropic funds from the U-M Life Sciences Institute.
Perspectives: Home Field Advantage
Director Roger Cone discusses how experts across disciplines tackle complex challenges together at the LSI, and how this collaborative spirit leads to scientific wins
Training Ground
In the LSI's collaborative environment, trainees build the skills to become team leaders
Open Gym
This open-source software program is using AI to level the playing field in animal behavior research
Metabolic Mash-up
Combining their diverse expertise, LSI researchers are putting a full-court press on metabolic health and disease
U-M researchers identify of new type of ‘disease-associated’ liver cells, with the potential to protect against MASH
The new findings offer a starting point to identify additional drivers of liver damage and a potential therapeutic target for metabolic dysfunction-associated steatohepatitis.
With philanthropic support, LSI launches new award to recognize the value of outstanding mentorship
The Marilyn Kroin Beck Mentorship Award celebrates LSI community members who demonstrate exceptional commitment to encouraging future scientists.
This genetic trick gives woodrats an evolutionary advantage against rattlesnake venom
LSI researchers have uncovered a clue explaining how woodrats have evolved potent immunity to rattlesnake bites.
Researchers unlock rare chemical transformation that can produce desired chemicals at higher yields with less waste
U-M chemists have opened a new mechanism for transforming molecules, offering a way to develop important molecules with fewer wasteful byproducts.
University of Michigan’s Natural Products Discovery Core Assessed “Awardable” for DARPA ERIS Marketplace
The LSI's Natural Products Discovery Core (NPDC) has achieved “Awardable” status through DARPA Expedited Research Implementation Series (ERIS) Marketplace, a transformative digital platform designed to accelerate acquisition velocity and advance national security innovation.
CATNIP for chemists: New data-driven tool broadens access to greener chemistry
A team led by LSI researchers has developed a new tool that removes a major barrier to wider adoption of biocatalysis, making greener chemistry more accessible.
New insights into protein recycling pathways shed light on how the brain forms memories
Researchers have uncovered new details in the complex cellular mechanism that is central to the brain’s ability to learn and form memories.
HIV’s route to infection is more flexible than previously believed, new U-M study finds
LSI researchers uncovered unexpected details of the process that HIV uses to hijack cells’ transportation systems. The new study also offers a new system for further investigations into viral infection.
Study uncovers how genetic mutations linked to childhood neurodegeneration cause essential cellular machine to break down
LSI researchers have determined how specific genetic mutations found in children with neurodegenerative diseases disrupt essential cellular processes.
New study reveals how shedding DNA allows pro-inflammatory immune cells to quiet inflammation
The immune system’s first responders can reverse their own inflammatory response by shedding tiny pieces of their identity, according to a new study from the LSI.
LSI faculty will explore new approaches to developing antiparasitics and preventing kidney disorders, with philanthropic funding
Two projects have been awarded Klatskin-Sutker Discovery funding, marking the fund’s ninth and tenth projects to receive support from the endowed fund.
Arsenal Bridge Ventures invests in U-M startup Courage Therapeutics to advance innovative weight regulation drugs
Courage Therapeutics, a University of Michigan spinout company developing medications for eating disorders and obesity, announced a significant investment from Arsenal Bridge Ventures. This seed investment will enable Courage Therapeutics to complete essential testing and development to advance its drug candidates to clinical trials.
New view of cellular delivery trucks reveals unexpected hitch
LSI researchers have uncovered an unexpected tactic that one class of proteins uses to ferry cargo to its cellular destination, offering understanding of a process that is fundamental to cell survival.
Variations in temperature and diet can affect this rodent’s ability to survive venomous snake bites
New research reveals that the power of a snake’s venom to incapacitate its prey may depend on more than just its potency, or even the prey’s tolerance for the toxin.
Perspectives: 'Amazingly Fertile Ground'
Two LSI faculty members discuss how their long-standing cross-discipline collaboration has helped their research flourish
Broadening the Research Lens
In the Aspirnaut Program at U-M, high school scientists see the full picture of their futures in STEM
Core Strength
The experts in the LSI’s cores don’t just advance research projects — they pioneer new science
Incubator for Innovation
A new crop of faculty is finding optimal growth conditions in the LSI’s interdisciplinary environment