Publications

Recent Articles | Articles (1995-2004) | Articles (1984-1994) | Articles (1977-1983) | Review Articles | Editorial Material | Notes

Recent Articles

Yana, I., Sagara, H., Takaki, S., Takatsu, K., Nakamura, K., Nakao, K., Katsuki, M., Taniguchi, S., Aoki, T., Sato, H., Weiss, S.J., & Seiki, M. (2007). Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells. Journal of Cell Science, 120, 1607-1614. PubMed Link

Yook, J.I., Li, X.Y., Ota, I., Hu, C., Kim, H.S., Kim, N.H., cha, S.Y., Ryu, J.K., Choi, Y.J., Kim, J., Fearon, E.R., & Weiss, S. J. (2006). A Wnt/Asin2/GSK3b cascade regulates Snail1 activity in breast cancer cells. Nature Cell Biology, 8, 1398-1406. PubMed Link

Hotary, K., Li, X.Y., Allen, E., Stevens, S.L., & Weiss, S. J. (2006). A cancer cell metalloprotease triad regulates the basement membrane transmigration program. Genes and Development, 20, 2673-2686. PubMed Link

Chun, T.H., Hotary, K.B., Sabeh, F., Saltiel, A.R., Holmbeck, K., Birkedal-Hansen, H., Allen, E.D., & Weiss, S. J. (2006). A pericellular collagenase directs the 3-dimensional development of white adipose tissue. Cell, 125, 577-591. PubMed Link

Zhai, Y. L., Hotary, K. B., Nan, B., Bosch, F. X., Munoz, N., Weiss, S. J., & Cho, K. R. (2005). Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion. Cancer Research, 65, 6543-6550. PubMed Link

Lehti, K., Allen, E., Birkedal-Hansen, H., Holmbeck, K., Miyake, Y., Chun, T. H., & Weiss, S. J. (2005). An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature. Genes & Development, 19, 979-991. PubMed Link

Yook, J. I., Li, X. Y., Ota, I., Fearon, E. R., & Weiss, S. J. (2005). Wnt-dependent regulation of the E-cadherin repressor snail. Journal of Biological Chemistry, 280, 11740-11748. PubMed Link

Filippov, S., Koenig, G. C., Chun, T. H., Hotary, K. B., Ota, I., Bugge, T. H., Roberts, J. D., Fay, W. P., Birkedal-Hansen, H., Holmbeck, K., Sabeh, F., Allen, E. D., & Weiss, S. J. (2005). MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells. Journal of Experimental Medicine, 202, 663-671.

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Articles (1995-2004)

Ailawadi, G., Eliason, J. L., Roelofs, K. J., Sinha, I., Hannawa, K. K., Kaldjian, E. P., Lu, G. Y., Henke, P. K., Stanley, J. C., Weiss, S. J., Thompson, R. W., & Upchurch, G. R. (2004). Gender differences in experimental aortic aneurysm formation. Arteriosclerosis Thrombosis and Vascular Biology, 24, 2116-2122. PubMed Link

Chun, T. H., Sabeh, F., Ota, I., Murphy, H., McDonagh, K. T., Holmbeck, K., Birkedal-Hansen, H., Allen, E. D., & Weiss, S. J. (2004). MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix. Journal of Cell Biology, 167, 757-767. PubMed Link

Sabeh, F., Ota, I., Holmbeck, K., Birkedal-Hansen, H., Soloway, P., Balbin, M., Lopez-Otin, C., Shapiro, S., Inada, M., Krane, S., Allen, E., Chung, D., & Weiss, S. J. (2004). Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. Journal of Cell Biology, 167, 769-781. PubMed Link

Hotary, K. B., Allen, E. D., Brooks, P. C., Datta, N. S., Long, M. W., & Weiss, S. J. (2003). Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. Cell, 114, 33-45. PubMed Link

Filippov, S., Caras, I., Murray, R., Matrisian, L. M., Chapman, H. A., Shapiro, S., & Weiss, S. J. (2003). Matrilysin-dependent elastolysis by human macrophages. Journal of Experimental Medicine, 198, 925-935. PubMed Link

Kleer, C. G., Cao, Q., Varambally, S., Shen, R. L., Ota, L., Tomlins, S. A., Ghosh, D., Sewalt, R. G. A. B., Otte, A. P., Hayes, D. F., Sabel, M. S., Livant, D., Weiss, S. J., Rubin, M. A., & Chinnaiyan, A. M. (2003). EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proceedings of the National Academy of Sciences of the USA, 100, 11606-11611. PubMed Link

Hotary, K. B., Yana, I., Sabeh, F., Li, X. Y., Holmbeck, K., Birkedal-Hansen, H., Allen, E. D., Hiraoka, N., & Weiss, S. J. (2002). Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity via MT1-MMP-dependent and -independent processes. Journal of Experimental Medicine, 195, 295-308. PubMed Link

Warner, R. L., Beltran, L., Younkin, E. M., Lewis, C. S., Weiss, S. J., Varani, J., & Johnson, K. J. (2001). Role of stromelysin 1 and gelatinase B in experimental acute lung injury. American Journal of Respiratory Cell and Molecular Biology, 24, 537-544. PubMed Link

Upchurch, G. R., Ford, J. W., Weiss, S. J., Knipp, B. S., Peterson, D. A., Thompson, R. W., Eagleton, M. J., Broady, A. J., Proctor, M. C., & Stanley, J. C. (2001). Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro. Journal of Vascular Surgery, 34, 76-82. PubMed Link

Jiang, A. X., Lehti, K., Wang, X., Weiss, S. J., Keski-Oja, J., Pei, D. Q. (2001). Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis. Proceedings of the National Academy of Sciences of the USA, 98, 13693-13698. PubMed Link

Hotary, K., Allen, E., Punturieri, A., Yana, I., & Weiss, S. J. (2000). Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. Journal of Cell Biology, 149, 1309-1323. PubMed Link

Punturieri, A., Filippov, S., Allen, E., Caras, I., Murray, R., Reddy, V., & Weiss S. J. (2000). Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages. Journal of Experimental Medicine, 192, 789-799. PubMed Link

Yana, I., & Weiss, S. J. (2000). Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases. Molecular Biology of the Cell, 11, 2387-2401. PubMed Link

Gibbs, D. F., Warner, R. L, Weiss, S. J., Johnson, K. J., & Varani, J. (1999). Characterization of matrix metalloproteinases produced by rat alveolar macrophages. American Journal of Respiratory Cell and Molecular Biology, 20, 1136-1144. PubMed Link

Rosenthal, E. L., Hotary, K., Bradford, C., & Weiss, S. J. (1999). Role of membrane type 1-matrix metalloproteinase and gelatinase A in head and neck squamous cell carcinoma invasion in vitro. Otolaryngology - Head and Neck Surgery, 121, 337-343.

Rosenthal, E. L., Johnson, T. M., Allen, E. D., Apel, I. J., Punturieri, A., & Weiss, S. J. (1998). Role of the plasminogen activator and matrix metalloproteinase systems iin epidermal growth factor and scatter factor-stimulated invasion of carcinoma cells. Cancer Research, 58, 5221-5230.

Hiraoka, N., Allen, E., Apel, I. J., Gyetko, M. R., & Weiss, S. J. (1998). Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins. Cell, 95, 365-377. PubMed Link

Pei, D. Q., & Weiss, S. J. (1996). Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. Journal of Biological Chemistry, 271, 9135-9140. PubMed Link

Shi, G. P., Chapman, H. A., Bhairi, S. M., Deleeuw, C., Reddy, V. Y., & Weiss, S. J. (1995). Molecular cloning of human cathepsin-O, a novel endoproteinase and homolog of rabbit-OC2. FEBS Letters, 357, 129-134.

Pei, D. Q., & Weiss, S. J. (1995). Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature, 375, 244-247. PubMed Link

Reddy, V. Y., Zhang, Q. Y., & Weiss, S. J. (1995). Pericellular mobilization of the tissue destructive cysteine proteinases, cathepsin-B, cathepsin-L, and cathepsin-S, by human monocyte-derived macrophages. Proceedings of the National Academy of Sciences of the USA, 92, 3849-3853. PubMed Link

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Articles (1984-1994)

Reddy, V. Y., Desrochers, P. E., Pizzo, S. V., Gonias, S. L., Sahakian, J. A., Levine, R. L., & Weiss, S. J. (1994). Oxidative dissociation of human alpha-2 macroglobulin tetramers into dysfunctional dimers. Journal of Biological Chemistry, 269, 4683-4691. PubMed Link

Pei, D. Q., Majmudar, G., & Weiss, S. J. (1994). Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3. Journal of Biological Chemistry, 269, 25849-25855. PubMed Link

Mulligan, M. S., Desrochers, P.E., Chinnaiyan, A. M., Gibbs, D. F., Varani, J., Johnson, K. J., & Weiss, S. J. (1993). In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinase-2. Proceedings of the National Academy of Sciences of the USA, 90, 11523-11527. PubMed Link

Desrochers, P. E., Mookhtiar, K., Vanwart, H. E., Hasty, K. A., & Weiss, S. J. (1992). Proteolytic inactivation of alpha-1 proteinase inhibitor and alpha-1 antichymotrypsin by oxidatively activated human neutrophil metalloproteinases. Journal of Biological Chemistry, 267, 5005-5012. PubMed Link

Huber, A. R., Kunkel, S. L., Todd, R. F., & Weiss, S. J. (1991). Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science, 254, 99-102. PubMed Link

Rice, W. G., & Weiss, S. J. (1990). Regulation of proteolysis at the neutrophil substrate interface by secretory leukoprotease inhibitor. Science, 249, 178-181. PubMed Link

Reddy, V. Y., Pizzo, S. V., & Weiss, S. J. (1989). Functional inactivation and structural disruption of human alpha-2 macroglobulin by neutrophils and eosinophils. Journal of Biological Chemistry, 264, 13801-13809. PubMed Link

Huber, A. R., & Weiss, S. J. (1989). Disruption of the subendothelial basement membrane during neutrophil diapedesis in an in vitro construct of a blood vessel wall. Journal of Clinical Investigation, 83, 1122-1136. PubMed Link

Trochelman, R. D., Weiss, S. J., Regiani, S., Liu, D. Y., & Todd, R. F. (1988). Expression of M03E antigen by cultured human umbilical vein endothelial cells (HUVEC) stimulated by phorbol myristate acetate (PMA) and related pharmacological inducers of protein kinase C. Cellular Immunology, 112, 89-103. PubMed Link

Kanofsky, J. R., Hoogland, H., Wever, R., & Weiss, S. J. (1988). Singlet oxygen production by human eosinophils. Journal of Biological Chemistry, 263, 9692-9696. PubMed Link

Weiss, S. J. (1986). Oxygen, ischemia and inflammation. Acta Physiologica Scandinavica, 126 (Suppl 548), 9-37. PubMed Link

Ossanna, P. J., Test, S. T., Matheson, N. R., Regiani, S., & Weiss, S. J. (1986). Oxidative regulation of neutrophil elastase alpha-1 proteinase inhibitor interactions. Journal of Clinical Investigation, 77, 1939-1951. PubMed Link

Weiss, S. J., Curnutte, J. T., & Regiani, S. (1986). Neutrophil-mediated solubilization of the subendothelial matrix - Oxidative and nonoxidative mechanisms of proteolysis used by normal and chronic granulomatous disease phagocytes. Journal of Immunology, 136, 636-641. PubMed Link

Myers, C. L., Weiss, S. J., Kirsh, M. M., Shepard, B. M., & Shlafer, M. (1986). Effects of supplementing hypothermic crystalloid cardioplegic solution with catalase, superoxide dismutase, allopurinol, or deferoxamine on functional recovery of globally ischemic and reperfused isolated hearts. Journal of Thoracic and Cardiovascular Surgery, 91, 281-289. PubMed Link

Peppin, G. J., & Weiss, S. J. (1986). Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils. Proceedings of the National Academy of Sciences of the USA, 83, 4322-4326. PubMed Link

Weiss, S. J., Test, S. T., Eckmann, C. M., Roos, D., & Regiani, S. (1986). Brominating oxidants generated by human eosinophils. Science, 234, 200-203. PubMed Link

Myers, C. L., Weiss, S. J., Kirsh, M. M., & Shlafer, M. (1985). Involvement of hydrogen peroxide and hydroxyl radical in the oxygen paradox - Reduction of creatine kinase release by catalase, allopurinol or deferoxamine, but not by superoxide dismutase. Journal of Molecular and Cellular Cardiology, 17, 675-684. PubMed Link

Weiss, S. J., Peppin, G., Ortiz, X., Ragsdale, C., & Test, S. T. (1985). Oxidative autoactivation of latent collagenase by human neutrophils. Science, 227, 747-749. PubMed Link

Passo, S. A., & Weiss, S. J. (1984). Oxidative mechanisms utilized by human neutrophils to destroy Escherichia coli. Blood, 63, 1361-1368. PubMed Link

Test, S. T., & Weiss, S. J. (1984). Quantitative and temporal characterization of the extracellular H202 pool generated by human neutrophils. Journal of Biological Chemistry, 259, 399-405. PubMed Link

Gabig, T. G., Lefker, B. A., Ossanna, P. J., & Weiss, S. J. (1984). Proton stoichiometry associated with human neutrophil respiratory-burst reactions. Journal of Biological Chemistry, 259, 3166-3171. PubMed Link

Test, S. T., Lampert, M. B., Ossanna, P. J., Thoene, J. G., & Weiss, S. J. (1984). Generation of nitrogen chlorine oxidants by human phagocytes. Journal of Clinical Investigation, 74, 1341-1349. PubMed Link

Weiss, S. J., & Regiani, S. (1984). Neutrophils degrade subendothelial matrices in the presence of alpha-1 proteinase inhibitor - Cooperative use of lysosomal proteinases and oxygen metabolites. Journal of Clinical Investigation, 73, 1297-1303. PubMed Link

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Articles (1977-1983)

Lampert, M. B., & Weiss, S. J. (1983). The chlorinating potential of the human monocyte. Blood, 62, 645-651. PubMed Link

Weiss, S. J., Lampert, M. B., & Test, S. T. (1983). Long-lived oxidants generated by human neutrophils - Characterization and bioactivity. Science, 222, 625-628. PubMed Link

Paredes, J. M., & Weiss, S. J. (1982). Human neutrophils transform proostaglandins by a myeloperoxidase-dependent mechanism. Journal of Biological Chemistry, 257, 2738-2740. PubMed Link

Weiss, S. J. (1982). Neutrophil-mediated methemoglobin formation in the erythrocyte - The role of superoxide and hydrogen peroxide. Journal of Biological Chemistry, 257, 2947-2953. PubMed Link

Weiss, S. J., Klein, R., Slivka, A., & Wei, M. (1982). Chlorination of taurine by human neutrophils - Evidence for hypochlorous acid generation. Journal of Clinical Investigation, 70, 598-607. PubMed Link

Weiss, S. J., & Slivka, A. (1982). Monocyte and granulocyte-mediated tumor cell destruction - A role for the hydrogen peroxide-myeloperoxidase chloride system. Journal of Clinical Investigation, 69, 255-262. PubMed Link

Weiss, S. J., & Ward, P. A. (1982). Immune complex-induced generation of oxygen metabolites by human neutrophils. Journal of Immunology, 129, 309-313. PubMed Link

Weiss, S. J., Young, J., Lobuglio, A. F., Slivka, A., & Nimeh, N. F. (1981). Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells. Journal of Clinical Investigation, 68, 714-721. PubMed Link

Slivka, A., Lobuglio, A. F., & Weiss, S. J. (1980). Potential role for hypochlorous acid in granulocyte-mediated tumor cell cytotoxicity. Blood, 55, 347-350. PubMed Link

Weiss, S. J., & Lobuglio, A. F. (1980). An oxygen-dependent mechanism of neutrophil-mediated cytotoxicity. Blood, 55, 1020-1024. PubMed Link

Weiss, S. J. (1980). The role of superoxide in the destruction of erythrocyte targets by human neutrophils. Journal of Biological Chemistry, 255, 9912-9917. PubMed Link

Weiss, S. J., Lobuglio, A. F., & Kessler, H. B. (1980). Oxidative mechanisms of monocyte-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the USA, 77, 584-587. PubMed Link

Weiss, S. J., & Sagone, A. L. (1979). Effect of oxidant stress on diamide-treated human granulocytes. Biochimica et Biophysica Acta, 585, 620-629. PubMed Link

Weiss, S. J., King, G. W., & Lobuglio, A. F. (1978). Superoxide generation by human monocytes and macrophages. American Journal of Hematology, 4, 1-8. PubMed Link

Weiss, S. J., Rustagi, P. K., & Lobuglio, A. F. (1978). Human granulocyte generation of hydroxyl radical. Journal of Experimental Medicine, 147, 316-323. PubMed Link

Weiss, S. J., King, G. W., & Lobuglio, A. F. (1977). Evidence for hydroxyl radical generation by human monocytes. Journal of Clinical Investigation, 60, 370-373. PubMed Link

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Review Articles

Weiss, S. J. (1989). Tissue destruction by neutrophils. New England Journal of Medicine, 320, 365-376.

Test, S. T., & Weiss, S. J. (1986). The generation and utilization of chlorinated oxidants by human neutrophils. Advances in Free Radical Biology and Medicine, 2, 91-116.

Weiss, S. J., & Lobuglio, A. F. (1982). Phagocyte-generated oxygen metabolites and cellular injury. Laboratory Investigation, 47, 5-18.

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Editorial Material

Weiss, S. J., & Peppin, G. J. (1986). Collagenolytic metalloenzymes of the human neutrophil - Characteristics, regulation, and potential function in vivo. Biochemical Pharmacology, 35, 3189-3197.

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Notes

Desrochers, P. E., Jeffrey, J. J., & Weiss, S. J. (1991). Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity. Journal of Clinical Investigation, 87, 2258-2265.

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