Publications

Recent Articles | Articles (2002-2006) | Articles (1997-2001)

Recent Articles

Li S, Liu C, Li N, Hao T, Han T, Hill DE, Vidal M, & Lin JD (2008). Genome-wide coactivation analysis of PGC-1α identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metabolism, in press.

Lin JD, Liu C, & Li S (2008). Integration of energy metabolism and the mammalian clock. Cell Cycle, 7, 453-457. Full Text (PDF)

Liu C, Li S, Liu T, Borjigin J, & Lin JD (2007). Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism. Nature, 447, 477-481. Full Text (PDF)

Articles (2002-2006)

Vianna, C.R., Huntgeburth, M., Coppari, R., Choi, C.S., Lin, J., Krauss, S., Barbatelli, G., Tzameli, I., Kim, Y.B., Cinti, S., Shulman, G.I., Spiegelman, B.M., & Lowell, B.B. (2006). Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance. Cell Metab, 4, 453-464. Full Text (PDF)

St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J.M., Rhee, J., Jager, S., Handschin, C., Zheng, K., Lin, J., Yang, W., Simon, D.K., Bachoo, R., & Spiegelman, B.M. (2006). Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell, 127, 397-408. Full Text (PDF)

*Sandri, M., *Lin, J., Handschin, C., Yang, W., Arany, Z.P., Lecker, S.H., Goldberg, A.L., & Spiegelman, B. M. (2006). PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci USA, 103, 16260-16265. * co-first author. Full Text (PDF)

Cooper, M.P., Qu, L., Rohas, L.M., Lin, J., Yang, W., Erdjument-Bromage, H., Tempst, P., & Spiegelman, B. M. (2006). Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1α/LRP130 complex. Genes Dev, 20, 2996-3009. Full Text (PDF)

Uldry, M., Yang, W., St-Pierre, J., Lin, J., Seale, P., & Spiegelman, B. M. (2006). Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab, 3, 333-341. Full Text (PDF)

Rhee, J., Ge, H., Yang, W., Fan, M., Handschin, C., Cooper, M., Lin, J., Li, C., & Spiegelman, B.M. (2006). Partnership of PGC-1alpha and HNF4alpha in the regulation of lipoprotein metabolism. J Biol Chem, 281, 14683-14690. Full Text (PDF)

Lin, J., Handschin, C., & Spiegelman, B. M. (2005). Metabolic control through the PGC-1 family of transcription coactivators. Cell Metabolism, 1, 361-370. (Review) Full Text (PDF)

Handschin, C., Lin, J., Rhee, J., Peyer, A. K., Chin, S., Wu, P. H., Meyer, U. A., & Spiegelman, B. M. (2005). Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1α. Cell, 122, 505-515. Full Text (PDF)

Lin, J., Yang, R. J., Tarr, P. T., Wu, P. H., Handschin, C., Li, S. M., Yang, W. L., Pei, L. M., Uldry, M., Tontonoz, P., Newgard, C. B., & Spiegelman, B. M. (2005). Hyperlipidemic effects of dietary saturated fats mediated through PGC-1β coactivation of SREBP. Cell, 120, 261-273. Full Text (PDF)

*Arany, Z., *He, H. M., *Lin, J., Hoyer, K., Handschin, C., Toka, O., Ahmad, F., Matsui, T., Chin, S., Wu, P. H., Rybkin, I. I., Shelton, J. M., Manieri, M., Cinti, S., Schoen, F. J., Bassel-Duby, R., Rosenzweig, A., Ingwall, J. S., & Spiegelman, B. M. (2005). Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle. Cell Metabolism, 1, 259-271. * co-first author. Full Text (PDF)

Andersen, G., Wegner, L., Yanagisawa, K., Rose, C. S., Lin, J., Glumer, C., Drivsholm, T., Borch-Johnsen, K., Jorgensen, T., Hansen, T., Spiegelman, B. M., & Pedersen, O. (2005). Evidence of an association between genetic variation of the coactivator PGC-1β and obesity. Journal of Medical Genetics, 42, 402-407. Full Text (PDF)

Lin, J., Wu, P. H., Tarr, P. T., Lindenberg, K. S., St-Pierre, J., Zhang, C. Y., Mootha, V. K., Jager, S., Vianna, C. R., Reznick, R. M., Cui, L. B., Manieri, M., Donovan, M. X., Wu, Z. D., Cooper, M. P., Fan, M. C., Rohas, L. M., Zavacki, A. M., Cinti, S., Shulman, G. I., Lowell, B. B., Krainc, D., & Spiegelman, B. M. (2004). Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice. Cell, 119, 121-135. Full Text (PDF)

Fan, M., Rhee, J., St-Pierre, J., Handschin, C., Puigserver, P., Lin, J., Jaeger, S., Erdjument-Bromage, H., Tempst, P., & Spiegelman, B. M. (2004). Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: Modulation by p38 MAPK. Genes & Development, 18, 278-289. Full Text (PDF)

St-Pierre, J., Lin, J., Krauss, S., Tarr, P. T., Yang, R. J., Newgard, C. B., & Spiegelman, B. M. (2003). Bioenergetic analysis of peroxisome proliferator-activated receptor γ coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells. Journal of Biological Chemistry, 278, 26597-26603. Full Text (PDF)

Lin, J., Tarr, P. T., Yang, R. J., Rhee, J., Puigserver, P., Newgard, C. B., & Spiegelman, B. M. (2003). PGC-1β in the regulation of hepatic glucose and energy metabolism. Journal of Biological Chemistry, 278, 30843-30848. Full Text (PDF)

Handschin, C., Rhee, J., Lin, J., Tarr, P. T., & Spiegelman, B. M. (2003). An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1α expression in muscle. Proceedings of the National Academy of Sciences of the USA, 100, 7111-7116. Full Text (PDF)

Zhou, B. Y., Lum, H. E., Lin, J., & Linzer, D. I. H. (2002). Two placental hormones are agonists in stimulating megakaryocyte growth and differentiation. Endocrinology, 143, 4281-4286. Full Text (PDF)

Lin, J., Puigserver, P., Donovan, J., Tarr, P., & Spiegelman, B. M. (2002). Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor. Journal of Biological Chemistry, 277, 1645-1648. Full Text (PDF)

Bhattacharyya, S., Lin, J., & Linzer, D. I. H. (2002). Reactivation of a hematopoietic endocrine program of pregnancy contributes to recovery from thrombocytopenia. Molecular Endocrinology, 16, 1386-1393. Full Text (PDF)

Lin, J., Wu, H., Tarr, P. T., Zhang, C. Y., Wu, Z. D., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., Lowell, B. B., Bassel-Duby, R., & Spiegelman, B. M. (2002). Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres. Nature, 418, 797-801. Full Text (PDF)

- back to top -

Articles (1997-2001)

Lefebvre, P., Lin, J., Linzer, D. I. H., & Cohen, I. (2001). Murine prolactin-like protein E synergizes with human thrombopoietin to stimulate expansion of human megakaryocytes and their precursors. Experimental Hematology, 29, 51-58. Full Text (PDF)

Puigserver, P., Rhee, J., Lin, J., Wu, Z. D., Yoon, J. C., Zhang, C. Y., Krauss, S., Mootha, V. K., Lowell, B. B., & Spiegelman, B. M. (2001). Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPAR gamma coactivator-1. Molecular Cell, 8, 971-982. PubMed Link

Lin, J., Toft, D. J., Bengtson, N. W., & Linzer, D. I. H. (2000). Placental prolactins and the physiology of pregnancy. Recent Progress in Hormone Research, 55, 37-52.

Lin, J., & Linzer, D. I. H. (1999). A novel megakaryocyte differentiation factor from mouse placenta. Trends in Cardiovascular Medicine, 9, 167-171. PubMed Link

Lin, J., & Linzer, D. I. H. (1999). Induction of megakaryocyte differentiation by a novel pregnancy-specific hormone. Journal of Biological Chemistry, 274, 21485-21489. Full Text (PDF)

Lin, J., & Linzer, D. I. H. (1998). Identification of trophoblast-specific regulatory elements in the mouse placental lactogen II gene. Molecular Endocrinology, 12, 418-427. Full Text (PDF)

Lin, J., Poole, J., & Linzer, D. I. H. (1997). Two novel members of the prolactin growth hormone family are expressed in the mouse placenta. Endocrinology, 138, 5535-5540. Full Text (PDF)

Lin, J., Poole, J., & Linzer, D. I. H. (1997). Three new members of the mouse prolactin growth hormone family are homologous to proteins expressed in the rat. Endocrinology, 138, 5541-5549. Full Text (PDF)

- back to top -