Kim Lab
Publications
Recent Articles | Articles (1993-2002) | Review Articles | Patents
Recent Articles
Simon, D., Madison, J., Connery, A., Thompson-Peer, K., Soskis, M., Ruvkun, G., Kaplan, J., and Kim, J.K. The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions. Cell (in press).
Manoharan, A.P. and Kim, J.K. MicroRNA target prediction algorithms. Current Protocols in Human Genetics (in press).
Wang, D., Kennedy, S., Conte, D., Kim, J.K., Gabel, H.W., Kamath, R.S., Mello, C.C., & Ruvkun, G. (2005). Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants. Nature, 436, 593-597. PubMed Link
Kim, J.K., Gabel, H.W., Kamath, R.S., Tewari, M., Pasquinelli, A., Rual, J.F., Kennedy, S., Dybbs, M., Bertin, N., Kaplan, J.M., Vidal,M., & Ruvkun, G. (2005). Functional genomic analysis of RNA interference in C.elegans. Science, 308, 1164-1167.PubMed Link
Kim, J., Krichevsky, A., Grad, Y., Hayes, G.D., Kosik, K.S., Church, G.M., & Ruvkun, G. (2004). Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proceedings of the National Academy of Sciences of the USA, 101, 360-365.PubMed Link
Grad, Y., Aach, J., Hayes, G.D., Reinhart, B.J., Church, G.M., Ruvkun, G., & Kim, J. (2003). Computational and experimental identification of C. elegans microRNAs. Molecular Cell, 11, 1253-1263. PubMed Link
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Articles (1993-2002)
Kim, J., Huang, W.P., Stromhaug, P.E., & Klionsky, D.J. (2002). Convergence of multiple autophagy and cytoplasm-to-vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation. Journal of Biological Chemistry, 277, 763-773. PubMed Link
Teter, S. A., Eggerton, K.P., Scott, S.V., Kim, J., Fischer, A.M., & Klionsky, D.J. (2001). Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase.Journal of Biological Chemistry, 276, 2083-2087.PubMed Link
Wang, C. W., Kim, J., Huang, W.P., Abeliovich, H., Stromhaug, P.E., Dunn, W.A., & Klionsky, D.J. (2001). Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways. Journal of Biological Chemistry, 276,30442-30451. PubMed Link
Kim, J.,Huang, W.P., & Klionsky, D.J. (2001). Membrane recruitment of Aut7p in the autophagy and cytoplasm-to-vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex. Journal of Cell Biology, 152, 51-64. PubMed Link
Kim, J.,Kamada, Y., Stromhaug, P.E., Guan, J., Hefner-Gravink, A., Baba, M., Scott, S. V., Ohsumi, Y., Dunn, W. A., & Klionsky, D. J.(2001). Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole. Journal of Cell Biology, 153, 381-396. PubMed Link
Scott, S.V., Guan, J., Hutchins, M.U., Kim, J., & Klionsky, D.J.(2001). Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway. Molecular Cell, 7, 1131-1141. PubMed Link
Huang, W.P., Scott,S.V.,Kim, J. , & Klionsky, D.J. (2000). The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways. Journal of Biological Chemistry, 275, 5845-5851. PubMed Link
Noda, T.,Kim, J., Huang, W.P., Baba, M., Tokunaga, C., Ohsumi, Y., & Klionsky, D.J. (2000). Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. Journal of Cell Biology, 148, 465-479. PubMed Link
Abeliovich, H., Dunn, W.A.,Kim, J. , & Klionsky, D.J. (2000). Dissection of autophagosome biogenesis into distinct nucleation and expansion steps. Journal of Cell Biology, 151, 1025-1033. PubMed Link
Kim, J.,Dalton, V.M., Eggerton, K.P., Scott, S.V., &Klionsky, D.J. (1999). Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways. Molecular Biology of the Cell, 10, 1337-1351. (Correction: U5-U6.) PubMed Link
Kim, J., Scott, S.V., Oda, M.N., & Klionsky, D.J. (1997). Transport of a large oligomeric protein by the cytoplasm to vacuole protein targeting pathway. Journal of Cell Biology, 137, 609-618. PubMed Link
Kim, J., Alizadeh, P., Harding, T., Hefner-Gravink, A., & Klionsky, D.J. (1996). Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: Potential commercial applications. Applied and Environmental Microbiology, 62, 1563-1569. PubMed Link
Aanstoot, H.J.,Kang, S.M.,Kim, J. , Lindsay, L.A., Roll, U., Knip, M., Atkinson, M., Mose-Larsen, P., Fey, S., Ludvigsson, J., Landin, M., Bruining, J., Maclaren, N., Akerblom, H.K., & Baekkeskov, S.(1996). Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD(65) and IA2 marks the early phases of autoimmune response in type 1 diabetes. Journal of Clinical Investigation, 97, 2772-2783.PubMed Link
Kim, J.,Namchuk, M., Bugawan, T., Fu, Q., Jaffe, M., Shi, Y.G., Aanstoot, H.J., Turck, C.W., Erlich, H., Lennon, V., & Baekkeskov, S.(1994). Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD(65) distinguish stiff man syndrome from insulin-dependent diabetes mellitus. Journal of Experimental Medicine, 180, 595-606.PubMed Link
Kim, J., Richter, W., Aanstoot, H.J., Shi, Y.G., Fu, Q., Rajotte, R., Warnock, G., & Baekkeskov, S. (1993). Differential expression of GAD(65) and GAD(67) in human, rat, and mouse pancreatic islets. Diabetes, 42, 1799-1808. PubMed Link
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Review Articles
Kim, J.,& Klionsky, D.J. (2000). Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. Annual Review of Biochemistry, 69, 303-342.
Kim, J., Scott, S.V., & Klionsky, D.J. (2000). Alternative protein sorting pathways. International Review of Cytology, 198,153-201.
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Patents
Kim, J., Gabel, H., Kamath, R., Ruvkun, G. (2005). Compositions and Methods that Modulate RNA Interference. Patent application filed. Serial No. 11/106,238.
Baekkeskov, S., Richter, W., Shi, Y., Namchuk, M., Kim, J. (1997). Reagents and Methods for the Diagnosis and Treatment of Diabetes and Stiff Man Syndrome. United States Patent 5,691,448
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