Publications

Recent Articles | Articles (1992-1997) | Review Articles

Recent Articles

Zhang, Y., Xu, J., Puscau, C., Kim, Y., Wang, X., Alam, H., and Hu, P.J. (2008). Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity. Developmental Biology 315:290-302. PubMed Link

Hu, P.J. Dauer (August 08, 2007), WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.144.1, www.wormbook.org PubMed Link

Hu, P.J., Xu, J., and Ruvkun, G. (2006). Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling. PLoS Genetics 2(7), e99. PubMed Link

Tewari, M.*, Hu, P. J.*, Ahn, J. S., Ayivi-Guedehoussou, N., Vidalain, P. O., Li, S. M., Milstein, S., Armstrong, C. M., Boxem, M., Butler, M. D., Busiguiina, S., Rual, J. F., Ibarrola, N., Chaklos, S. T., Bertin, N., Vaglio, P., Edgley, M. L., King, K. V., Albert, P. S., Vandenhaute, J., Pandey, A., Riddle, D. L., Ruvkun, G., & Vidal, M. (2004). Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network. Molecular Cell 13:469-482. *equal contribution PubMed Link

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Articles (1992-1997)

Hu, P. J., Shih, I. M., Hutchins, G. M., & Hellmann, D. B. (1997). Polyarteritis nodosa of the pericardium: antemortem diagnosis in a pericardiectomy specimen. Journal of Rheumatology 24:2042-2044. PubMed Link

Logan, S. K., Falasca, M., Hu, P., & Schlessinger, J. (1997). Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway. Molecular and Cellular Biology 17:5784-5790. PubMed Link

Spivak-Kroizman, T., Mohammadi, M., Hu, P., Jaye, M., Schlessinger, J., & Lax, I. (1994). Point mutation in the fibroblast growth factor receptor eliminates phosphatidylinositol hydrolysis without affecting neuronal differentiation of PC12 cells. Journal of Biological
Chemistry 269:14419-14423. PubMed Link

Hu, P., & Schlessinger, J. (1994). Direct association of p110β phosphatidylinositol 3-kinase with p85 is mediated by an N-terminal fragment of p110β. Molecular and Cellular Biology 14:2577-2583. PubMed Link

Piccione, E., Case, R. D., Domchek, S. M., Hu, P., Chaudhuri, M., Backer, J. M., Schlessinger, J., & Shoelson, S. E. (1993). Phosphatidylinositol 3-kinase p85 SH2 domain specificity defined by direct phosphopeptide SH2 domain binding. Biochemistry 32:3197-3202. PubMed Link

Shoelson, S. E., Sivaraja, M., Williams, K. P., Hu, P., Schlessinger, J., & Weiss, M. A. (1993). Specific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activation. EMBO Journal 12:795-802. PubMed Link

Felder, S., Zhou, M., Hu, P., Urena, J., Ullrich, A., Chaudhuri, M., White, M., Shoelson, S. E., & Schlessinger, J. (1993). SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange. Molecular and Cellular Biology 13:1449-1455. PubMed Link

Hu, P., Mondino, A., Skolnik, E. Y., & Schlessinger, J. (1993). Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85. Molecular and Cellular Biology 13:7677-7688. PubMed Link

Backer, J. M., Myers, M. G., Shoelson, S. E., Chin, D. J., Sun, X. J., Mirapeix, M., Hu, P., Margolis, B., Skolnik, E. Y., Schlessinger, J., & White, M. F. (1992). Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation. EMBO Journal 11:3469-3479. PubMed Link

Hu, P., Margolis, B., Skolnik, E. Y., Lammers, R., Ullrich, A., & Schlessinger, J. (1992). Interaction of phosphatidylinositol 3-kinase associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Molecular and Cellular Biology 12:981-990. PubMed Link

Li, W., Hu, P., Skolnik, E. Y., Ullrich, A., & Schlessinger, J. (1992). The SH2 and SH3 domain containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors. Molecular and Cellular Biology 12:5824-5833. PubMed Link

Margolis, B.*, Hu, P.*, Katzav, S., Li, W., Oliver, J. M., Ullrich, A., Weiss, A., & Schlessinger, J. (1992). Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature 356:71-74. *equal contribution PubMed Link

Myers, M. G., Backer, J. M., Sun, X. J., Shoelson, S., Hu, P., Schlessinger, J., Yoakim, M., Schaffhausen, B., & White, M. F. (1992). IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85. Proceedings of the National Academy of Sciences of the USA 89:10350-10354. PubMed Link

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Review Articles

Hu, P., Margolis, B., & Schlessinger, J. (1993). Vav - a potential link between tyrosine kinases and Ras-like GTPases in hematopoietic cell signaling. Bioessays 15:179-183.

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