Garneau-Tsodikova Lab
Content:
Discoveries
Garneau-Tsodikova lab identifies a novel tryptophan 2,3-dioxygenase
In May 2008, the Garneau-Tsodikova lab published a manuscript in an issue of Molecular Biosystems for "Emerging Investigators" on TioF. TioF is a novel tryptophan 2,3-dioxygenase involved in the formation of the key chromophore 3-hydroxyquinaldic acid of thiocoraline. This work represents the first in vitro characterization of an enzyme involved in the biosynthesis of this bisintercalator anticancer agent.
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