Center for Structural Biology
Comprehensive cloning, protein purification and macromolecular X-ray crystallography — supporting discovery science and therapeutic projects.
The Center for Structural Biology is a comprehensive structural biology resource for researchers at the University of Michigan and beyond. Part of the U-M Life Sciences Institute, the CSB includes:
- a high-throughput protein laboratory for protein engineering
- protein purification facilities for small- and large-scale protein production
- macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules
- an X-ray facility with access to high energy synchrotron radiation
Our dedicated staff scientists have years of academic and industry experience, allowing us to provide expert guidance to researchers through every stage of a project — collaborating and consulting with researchers who use the facilities. We also have a programmatic collaboration with the LSI's Center for Chemical Genomics, allowing the determination of target proteins in complex with compounds identified in high-throughput screening. Our services are available to U-M researchers as well as to outside academic and industry partners.
